Chrna4 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comChrna4 ELISA Kit for Rat(Rattus norvegicus)

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Chrna4 (Gene name),

Neuronal acetylcholine receptor subunit alpha-4 (Protein name ), ACHA4_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Chrna4(Acra4);

Protein name:

Neuronal acetylcholine receptor subunit alpha-4;

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-4 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly.

Function:

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Subcellular Location:

Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

630

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

630:

VIDRIFLWMF | IIVCLLGTVG | LFLPPWLAAC |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.9697

String:

P09483

KEGG:

rno:25590

Pfam:

PF02931

SMR:

P09483

Uniprot:

P09483

FOR

ELISA Kit for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

E1913m

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Packing:

96T

ELISA Kit for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

E1913c

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96T

ELISA Kit for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

E1913h

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96T

ELISA Kit for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

E1913r

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96T

CLIA Kit for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

U1913m

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Packing:

96T

CLIA Kit for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

U1913h

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96T

CLIA Kit for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

U1913c

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Packing:

96T

CLIA Kit for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

U1913r

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96T

Polyclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

P1913Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

P1913Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-4

Cat.:

P1913Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-4

Protein for Rat Neuronal acetylcholine receptor subunit alpha-4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Members of a nicotinic acetylcholine receptor gene family are expressed in different regions of the mammalian central nervous system."
Goldman D.J. , Deneris E.S. , Luyten W. , Kochhar A. , Patrick J. , Heinemann S.F.
Cell48:965-973(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA-4-1);NUCLEOTIDE SEQUENCE [MRNA] OF 5-630 (ISOFORM ALPHA-4-2)
strain: Sprague-Dawley.
tissue: Hippocampus.
tissue: Hypothalamus.
2.

Hartley M. , Goldman D.J. , Heinemann S.F.
Submitted (1998-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
3.

Boulter J. , Deneris E.S. , Evans K. , Heinemann S.F.
Submitted (1997-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA-4-2)
4.

"Neuronal nicotinic acetylcholine receptor beta-subunit is coded for by the cDNA clone alpha 4."
Whiting P. , Esch F. , Shimasaki S. , Lindstrom J.
FEBS Lett.219:459-463(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 31-47
5.

"A highly conserved cytoplasmic cysteine residue in the alpha4 nicotinic acetylcholine receptor is palmitoylated and regulates protein expression."
Amici S.A. , McKay S.B. , Wells G.B. , Robson J.I. , Nasir M. , Ponath G. , Anand R.
J. Biol. Chem.287:23119-23127(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-273;SUBCELLULAR LOCATION

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